Sourav Banerjee, Tiantian Wei, Jue Wang, Jenna J. Lee, Haydee L. Gutierrez, Owen Chapman, Sandra E. Wiley, Joshua E. Mayfield, Vasudha Tandon, Edwin F. Juarez, Lukas Chavez, Ruqi Liang, Robert L. Sah, Caitlin Costello, Jill P. Mesirov, Laureano de la Vega, Kimberly L. Cooper, Jack E. Dixon, Junyu Xiao, Xiaoguang Lei Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proceedings of the National Academy of Sciences, 116(49), 24881-24891. (2019).

Yujuan Cai, Yang Hai, Masao Ohashi, Cooper S. Jamieson, Marc Garcia-Borras, K. N. Houk, Jiahai Zhou, Yi Tang Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nature Chemistry, 11(9), 812-820. (2019).

Hao Cao, Lichao Sun, Ying Huang, Xin Liu, Dong Yang, Tengfei Liu, Xiaojing Jia, Boting Wen, Tianyi Gu, Fengzhong Wang, Fengjiao Xin Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester–Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus. ACS Catalysis, 9(3), 1739-1747. (2019).

Yixin Cen, Warispreet Singh, Mamatjan Arkin, Thomas S. Moody, Meilan Huang, Jiahai Zhou, Qi Wu, Manfred T. Reetz Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution. Nature Communications, 10(1), 3198. (2019).

Guihong Cha, Zimin Chen, Ran Mo, Guangwen Lu, Beile Gao The novel regulators CheP and CheQ control the core chemotaxis operon cheVAW in Campylobacter jejuni. Molecular microbiology, 111(1), 145-158. (2019).

Danqi Chen, Yuehong Chen, Fulin Lian, Liu Chen, Yanlian Li, Danyan Cao, Xin Wang, Lin Chen, Jian Li, Tao Meng, Min Huang, Meiyu Geng, Jingkang Shen, Naixia Zhang, Bing Xiong Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction. European Journal of Medicinal Chemistry, 163, 597-609. (2019).

Danqing Chen, Shuguang Tan, Hao Zhang, Haiyuan Wang, Weiwu He, Rui Shi, Zhou Tong, Jianhua Zhu, Hao Cheng, Shan Gao, Yan Chai, Jianxun Qi, Minghui Xiao, Jinghua Yan, George F. Gao The FG Loop of PD-1 Serves as a “Hotspot” for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. iScience, 14, 113-124. (2019).

Deheng Chen, Tian Lu, Ziqin Yan, Wenchao Lu, Feilong Zhou, Xilin Lyu, Biling Xu, Hualiang Jiang, Kaixian Chen, Cheng Luo, Yujun Zhao Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins. European Journal of Medicinal Chemistry, 182, 111633. (2019).